C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
167/139, 167/37,
C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C12N 5/12 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2039230
The present invention involves the use of monoclonal antibodies specific for Oncostatin M to inhibit the growth potentiating effect of Oncostatin M on Kaposi's Sarcoma associated with AIDS. In particular neutralizing anti-Oncostatin M antibodies inhibit the growth of Kaposi's Sarcoma which is potentiated and maintained by Oncostatin M or a factor found in conditioned media of an HTLV-II transformed T cell line.
Gallo Robert C.
Linsley Peter S.
Nakamura Shuji
Radka Susan F.
Salahuddin Syed Z.
Gowling Lafleur Henderson Llp
Oncogen Limited Partnership
The United States Government As Represented By The Secretary Of The Dep Artment Of Health And
LandOfFree
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