Monoclonal antibodies, their production and use

C - Chemistry – Metallurgy – 12 – P

Patent

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Details

C12P 21/08 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/46 (2006.01) C12N 5/12 (2006.01)

Patent

CA 2069439

2069439 9109134 PCTABS00005 The present invention provides a hybrid monoclonal antibody having specificities against a human cancer cell and a prodrug-activating enzyme, a polydoma which produces said antibody and an anti-human-cancer-protein complex comprising said antibody and prodrug activating enzyme which is immunologically coupled thereto, and methods of using said antibody in combination with anticancer prodrug for therapy of cancer.

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