Monoclonal antibodies to a new antigenic marker in...

Details Monoclonal antibodies to a new antigenic marker in... Monoclonal antibodies to a new antigenic marker in...

C - Chemistry, Metallurgy

12

N

167/139, 167/45,

C12N 5/20 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1339607

Monoclonal antibodies to prostatic cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies show specificity for a non-soluble, membrane associated, organ specific antigenic determinant limited in its distribution to human prostate epithelial cells and normal prostatic epithelial cells. The monoclonal antibodies, specifically, 7E11 monoclonal antibodies, can be used diagnostically and therapeutically.

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