C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/10 (2006.01) C07K 14/16 (2006.01) C12N 5/20 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2431321
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
L'invention concerne de nouveaux anticorps monoclonaux qui peuvent être utilisés pour la détection du virus de l'immunodéficience humaine (VIH). Ces anticorps présentent un degré de sensibilité exceptionnellement élevé, un champ de spécificité remarquablement large, et se lient avec de nouveaux épitopes communs ne produisant pas de réaction croisée. Ces anticorps monoclonaux conviennent en particulier pour la détection de l'antigène VIH-1 et de l'antigène capsidique VIH2 dans un échantillon prélevé sur un patient.
Hunt Jeffrey C.
Konrath John G.
Lou Sheng C.
Qiu Xiaoxing
Scheffel James W.
Abbott Laboratories
Mbm Intellectual Property Law Llp
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