Monoclonal antibodies to segments of hiv-1 reverse...

C - Chemistry – Metallurgy – 07 – K

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C07K 16/40 (2006.01) C07K 16/10 (2006.01) C12N 5/18 (2006.01) G01N 33/569 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2066171

2066171 9105066 PCTABS00004 Hybridoma cell lines which produce monoclonal antibodies that specifically bind to antigenic recognition sites on segments of HIV-1 reverse transcriptase, the cell lines being selected from the group consisting of HB10243, HB10244, HB10245, HB10246, HB10247, HB10248. A method of preparing a monoclonal antibody which comprises culturing hybridoma selected from the group consisting of HB10243, HB10244, HB10245, HB10246, HB10247, HB10248 in a suitable culture medium and recovering antibody. A method of detecting segments of HIV-1 reverse transcriptase in a test sample. A diagnostic system for detecting the presence and amount of segments of HIV-1 reverse transcriptase in a test sample.

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