Monoclonal antibodies to the light chain region of human...

Details Monoclonal antibodies to the light chain region of human... Monoclonal antibodies to the light chain region of human...

C - Chemistry, Metallurgy

12

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167/139, 195/78,

C12P 21/08 (2006.01) A61K 39/395 (2006.01) C07K 16/40 (2006.01) C12N 5/18 (2006.01) C12N 9/64 (2006.01) C12S 3/22 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1315716

MONOCLONAL ANTIBODIES TO THE LIGHT CHAIN REGION OF HUMAN FACTOR XII AND METHODS OF PREPARING AND USING THE SAME Abstract Novel hybrid cell lines produce monoclonal antibody to the light chain region of human factor XII. Three such cell lines, ATCC #HB-9703 through ATCC #HB-9704, are formed by fusing SP2/0-Ag14 myeloma cells with spleen cells from BALB/c AnSkh mice immunized with human factor XIIf. The monoclonal antibodies may be used, for example, for remov- ing human factor XII fragments containing the factor XII light chain, from liquids, e.g. blood plasma products.

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