C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) C07K 14/705 (2006.01) C12N 5/20 (2006.01) G01N 33/53 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2561830
The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The monoclonal antibody reacts with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cell.
La présente invention concerne un anticorps monoclonal et des cellules hybridomes et antigènes correspondants appropriés pour l'isolement de cellules embryonnaires du sang maternel. L'anticorps monoclonal de l'invention réagit avec un antigène de surface présent dans les érythrocytes du foetus, y compris les cellules précurseurs nuclées de ces derniers, mais ne réagit pas avec des antigènes de surface présents dans une cellule érythrocyte d'adulte.
Albert Winfried
Hollmann Christiane
Stachelhaus Stefan
Zimmermann Silke
Adnagen Ag
Mcfadden Fincham
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