Monoclonal antibody anti .alpha.v-integrin and its use to...

Details Monoclonal antibody anti .alpha.v-integrin and its use to... Monoclonal antibody anti .alpha.v-integrin and its use to...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) C12N 5/20 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2319160

The invention relates to a novel monoclonal antibody and a hybridoma cell line producing said antibody. The monoclonal antibody, a preferred embodiment of which is named 14D9.F8, has the following properties: reacting only with the .alpha.v-chain of human .alpha.v-integrins, and inhibiting selectively the attachment to the integrin substrate fibronectin of the .alpha.v.beta.6- integrin bearing cell.

L'invention concerne un nouvel anticorps monoclonal et une lignée cellulaire d'hybridome produisant ledit anticorps. L'anticorps monoclonal, dont une forme de réalisation préférée est appelée 14D9.F8, présente les propriétés suivantes: il ne réagit qu'avec la chaîne .alpha.v des intégrines .alpha.v humaine; et il inhibe de façon sélective la fixation au substrat d'intégrine fibronectine de la cellule portant l'intégrine .alpha.v.beta.6.

Affiliated with

Also associated with

Rating

Monoclonal antibody anti .alpha.v-integrin and its use to... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibody anti .alpha.v-integrin and its use to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibody anti .alpha.v-integrin and its use to... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1615758