C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/32 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12N 5/10 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2706549
The present inventors have succeeded in producing anti-AXL antibodies with specific functions. The present inventors also discovered that the antibodies have an angiogenesis-suppressive effect and an antitumor effect, and thereby completed the present invention. The anti-AXL antibodies of the present invention are useful as angiogenesis inhibitors and agents for inducing or inhibiting phosphorylation activity.
Un anticorps anti-AXL ayant une fonction spécifique peut être obtenu avec succès. On a découvert que l'anticorps a une activité anti-angiogénique et une activité anti-cancéreuse. L'anticorps anti-AXL est utile en tant qu'agent anti-angiogénique ou en tant qu'agent pour induire ou inhiber une activité de phosphorylation.
Kitazawa Takehisa
Miyamoto Hajime
Nagahashi Shigehisa
Suzuki Tsukasa
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Chugai Seiyaku Kabushiki Kaisha
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