Monoclonal antibody capable of binding to heparin-binding...

Details Monoclonal antibody capable of binding to heparin-binding... Monoclonal antibody capable of binding to heparin-binding...

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) A61K 39/395 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01) C12N 1/15 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2707689

Medicaments for treating diseases related to HB-EGF escalation are in demand. The present invention provides a monoclonal antibody or an antibody fragment thereof which binds to a cell membrane-bound HB-EGF, a membrane type HB-EGF and a secretory HB-EGF.

L'invention concerne un agent médicinal pour le traitement d'une maladie caractérisée par un niveau accru de HB-EGF. L'invention concerne ainsi un anticorps monoclonal capable de se lier à un HB-EGF qui est relié à une membrane cellulaire, un HB-EGF ancré à une membrane et un HB-EGF sécrété ou un fragment de l'anticorps monoclonal.

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