Monoclonal antibody capable of binding to heparin-binding...

Details Monoclonal antibody capable of binding to heparin-binding... Monoclonal antibody capable of binding to heparin-binding...

C - Chemistry, Metallurgy

07

K

C07K 16/22 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12N 15/02 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2654572

There has been a demand for a pharmaceutical for the treatment of a disease characterized by the increase in an HB-EGF. Disclosed is a monoclonal antibody capable of binding to an HB-EGF binding to a cell membrane, a membrane-anchored HB-EGF or a secreted HB-EGF or a fragment of the antibody.

Il existe un besoin de produits pharmaceutiques permettant le traitement d'une maladie caractérisée par l'accroissement de HB-EGF. L'invention concerne donc un anticorps monoclonal, ou un fragment dudit anticorps, capable de se lier à un HB-EGF de liaison à une membrane cellulaire, à un HB-EGF fixé à une membrane ou à un HB-EGF sécrété.

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