Monoclonal antibody for differentiating hiv-2 from hiv-1...

C - Chemistry – Metallurgy – 12 – N

Patent

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167/44, 195/1.10

C12N 5/18 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2009198

A mouse monoclonal antibody is provided which detects HIV-2 seropositive individuals and differentiates them from HIV-1 seropositive individuals. The monoclonal antibody is specific for an epitope of HIV-2 gp41 which lies outside the characterized immunodominant region. The epitope recognized by the monoclonal antibody has the amino acid sequence HTTVPW.

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