Monoclonal antibody having specificity for the double...

Details Monoclonal antibody having specificity for the double... Monoclonal antibody having specificity for the double...

G - Physics

01

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167/37, 195/1.11

G01N 33/577 (2006.01) A61K 39/395 (2006.01) C07K 16/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 1216808

Abstract of the Disclosure Monoclonal antibodies having conformation-dependent specificity for native dsDNA, as exemplified by the IgM antibody produced by murine hybridoma ATCC No. HB 8329, have been prepared. These antibodies may be bound to double-stranded DNA to form immune complexes and thus are useful in immunodiagnostic tests to detect DNA duplex formation by DNA hybridization.

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