C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/06 (2006.01) C07K 16/18 (2006.01) C12N 5/10 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2340318
Hybridomas which are fused cell obtained from antibody-producing cells isolated from a mammal immunized with human cells and a myeloma cell line and produce a monoclonal antibody inhibiting the liberation of human cell ATP; and the monoclonal antibody obtained by isolating and purifying from these hybridomas.
La présente invention concerne des hybridomes, qui sont constitués par des cellules obtenues par fusion à partir de cellules produisant des anticorps et isolées à partir d'un mammifère immunisés au moyen de cellules humaines, et une lignée cellulaire myélomateuse. Ces hybridomes produisent un anticorps monoclonal qui inhibe la libération d'ATP humain. L'invention concerne également l'anticorps obtenu par isolement et purification de ces hybridomes.
Hazama Akihiro
Okada Yasunobu
Japan Science And Technology Corporation
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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