Monoclonal antibody mixtures and use thereof for enhanced...

Details Monoclonal antibody mixtures and use thereof for enhanced... Monoclonal antibody mixtures and use thereof for enhanced...

G - Physics

01

N

167/139, 167/37

G01N 33/577 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/74 (2006.01) G01N 33/76 (2006.01)

Patent

CA 1222449

MONOCLONAL, ANTIBODY MIXTURES AND USE THEREOF FOR ENHANCED SENSITIVITY IMMUNOASSAYS Abstract of the Disclosure Mixtures of monoclonal antibodies which contain effective assaying amounts of each of at least two monoclonal anti- bodies that bind to different antigenic sites on the antigen and are capable under appropriate conditions of binding simultaneously to an antigen are useful in enhanced sensitivity assays for the antigen. By utilizing such mixtures in diagnostic assays for important antigens such as the polypeptide human chorionic gonadotropic enhanced sensitivity can be achieved as compared with assays em- ploying individual monoclonal antibodies.

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