C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/40 (2006.01) A61K 39/395 (2006.01) A61P 19/02 (2006.01) A61P 35/00 (2006.01) C07K 16/46 (2006.01) C12N 5/20 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2447313
The present invention relates to a monoclonal antibody capable of neutralising cathepsin B. In particular, the present invention is concerned with the use of such an antibody for the detection or treatment of diseases associated with an over-expression and/or excessive activity of cathepsin B, such as cancer or arthritis.
L'invention concerne un anticorps monoclonal capable de neutraliser la cathépsine B. L'invention concerne plus précisément l'utilisation d'un tel anticorps pour la détection ou le traitement de maladies associées à une sur-expression et/ou une activité excessive de la cathépsine B, telles que le cancer ou l'arthrite.
Bestagno Marco
Burrone Oscar R.
Fan Xiaohui
Kopitar Jerala Natasa
Kos Janko
Borden Ladner Gervais Llp
Krka Tovarna Zdravil D.d. Novo Mesto
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