Monoclonal antibody reacting specifically with fas ligand...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/13 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/20 (2006.01) C12N 15/06 (2006.01) G01N 33/543 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2215905

A monoclonal antibody reacting specifically with Fas ligands or the active fragment thereof; a process for producing a monoclonal antibody reacting specifically with Fas ligands; hybridomas producing a monoclonal antibody which reacts specifically with Fas ligands existing on the cell surface or soluble ligands; a method for detecting Fas ligands in a solution; and a kit for detecting Fas ligands which comprises a combination of monoclonal antibodies for Fas ligands.

L'invention concerne: un anticorps monoclonal qui réagit spécifiquement avec des ligands Fas ou une partie active de ces ligands; un procédé qui permet de produire un anticorps monoclonal réagissant spécifiquement avec les ligands Fas; des hybridomes produisant un anticorps monoclonal qui réagit spécifiquement avec des ligands Fas situés à la surface de cellules ou avec des ligands solubles; un procédé qui permet de déceler les ligands Fas dans une solution; et un nécessaire pour déceler les ligands Fas, dans lequel on trouve une combinaison d'anticorps monoclonaux contre les ligands Fas.

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