Monoclonal antibody specific for a mammary tumor cytoplasmis...

Details Monoclonal antibody specific for a mammary tumor cytoplasmis... Monoclonal antibody specific for a mammary tumor cytoplasmis...

C - Chemistry, Metallurgy

12

N

195/1.109

C12N 5/00 (2006.01) C07K 16/30 (2006.01) C12P 21/00 (2006.01)

Patent

CA 1238285

MONOCLONAL ANTIBODY SPECIFIC FOR A MAMMARY TUMOR CYTOPLASMIC ANTIGEN ABSTRACT OF THE DISCLOSURE A monoclonal antibody is produced which is specific for an antigen found almost exclusively in the cytoplasm of human mammary tumor cells. Animals are inoculated with human mammary tumor cells or cell material, and spleen cells obtained from the animals are fused with myeloma cells to produce hybridomas. The hybridomas are cultured as monoclones, and antibodies obtained from the individual clones are tested for their reactivity with cytoplasms of several human mammary tumor cell lines and mammary tumor tissues. A clone which produces an antibody that reacts with the cytoplasm of most human mammary tumor cells is selected for further culturing to produce the antibody, and the antibody is obtained from the culture growth medium or from ascitic fluid of an animal bearing a tumor of the hybridoma. The antibody is useful in diagnosing mammary tumors.

496241

Affiliated with

Also associated with

Rating

Monoclonal antibody specific for a mammary tumor cytoplasmis... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Monoclonal antibody specific for a mammary tumor cytoplasmis..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Monoclonal antibody specific for a mammary tumor cytoplasmis... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1246724