C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 14/705 (2006.01) C12N 5/18 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2190262
An antigen which is specific to vascular endothelium is described. Described is a cell surface antigen which consists of four subunits, of 190, 145, 125 and 110 kd as determined by SDS-PAGE under reducing conditions as is a monoclonal antibody specific to this antigen. Uses, both diagnostic and therapeutic, are also described.
L'invention concerne un antigène spécifique à l'endothélium vasculaire. Elle concerne également un antigène de surface cellulaire constitué de quatre sous unités de 190, 145, 125 et 110 kd déterminées par SDS-PAGE dans des conditions de réduction tout comme un anticorps monoclonal spécifique contre cet antigène. En outre, l'invention concerne ses utilisations à la fois diagnostiques et thérapeutiques.
Garin-Chesa Pilar
Old Lloyd
Rettig Wolfgang J.
Sanz-Moncasi Maria Pilar
Stockert Elisabeth
Ludwig Institute For Cancer Research
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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