C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/26 (2006.01) A61K 39/395 (2006.01) A61P 35/02 (2006.01) C07K 16/28 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2169950
It is the objective and purpose of the present invention to provide a monoclonal antibody having the property of causing apoptosis on myeloid cells. This invention relates to a monoclonal antibody having the property of causing apoptosis on myeloid cells, and fragments thereof, and furthermore relates to a hybridoma producing the monoclonal antibody. Since the monoclonal antibodies of the present invention are useful as antibodies recognizing and identifying antigens causing apoptosis on myeloid cells specifically and besides have the property of causing apoptosis on myeloid cells, they may be used as medicine useful in the field of remedies for myelocytic leukemia utilizing the property.
L'invention concerne un anticorps monoclonal qui induit l'apoptose dans la cellule myélocytique, un fragment de l'anticorps et un hybridome qui produit l'anticorps. L'anticorps est utile en ce qu'il reconnaît de manière spécifique un antigène ou autre induisant l'apoptose dans la cellule myélocytique et le distingue et l'identifie. En outre, l'anticorps peut être utilisé comme médicament efficace dans le domaine du traitement de la leucémie myélocytique en utilisant l'activité de l'apoptose induite dans la cellule myélocytique.
Chugai Seiyaku Kabushiki Kaisha
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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