Monoclonal human tumor-specific antibody

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/00 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2680914

Provided are novel human tumor-specific antibodies as well as fragments, derivatives and variants thereof that recognize tumor-associated antigen NY-ESO-1. In addition, pharmaceutical compositions comprising such antibodies and mimics thereof in the treatment of tumors are described.

L'invention concerne des nouveaux anticorps humains spécifiques d'une tumeur ainsi que des fragments, dérivés et variants de ceux-ci qui reconnaissent un antigène associé à la tumeur, le NY-ESO-1. De plus, l'invention concerne des compositions pharmaceutiques comprenant de tels anticorps et des mimétiques de ceux-ci, utilisées dans le traitement de tumeurs.

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