Monoclonal igm antibodies and method of preparation

C - Chemistry – Metallurgy – 12 – N

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C12N 5/02 (2006.01) A61K 39/395 (2006.01) C07K 16/08 (2006.01) C12N 15/00 (2006.01) C12P 21/00 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/58 (2006.01)

Patent

CA 1240937

Abstract of the Disclosure This invention relates to the preparation of monoclonal IgM antibodies particularly IgM virus antibodies and the detection of antigens or antiantigen IgM immunoglobulin in biological fluids by improved immunoassay techniques employing monoclonal IgM antigen specific antibodies and a readable label, preferably a biotin-avidin based, detection system. In a specific embodiment, this invention relates to monoclonal IgM virus/antigen type common and type specific herpes sim- plex antibodies and their diagnostic use.

432873

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