Monoclonal recombinant anti-rhesus d (d7c2) antibody

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/34 (2006.01) C12N 15/86 (2006.01) C12N 15/866 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2198935

Cloning of DNA fragments which code for the light chain or the heavy chain variable domain of the D7C2 monoclonal antibody within a baculovirus. The invention also concerns the expression of these DNA fragments in insect host cells, the anti-rhesus D recombinant monoclonal antibody so obtained and its use.

L'invention est relative au clonage de fragments d'ADN qui codent pour le domaine variable de la chaîne légère ou de la chaîne lourde de l'anticorps monoclonal D7C2, dans un baculovirus, à leur expression dans des cellules-hôte d'insecte, à l'anticorps monoclonal recombinant anti-Rhésus D obtenu de la sorte, et à ses utilisations.

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