C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/78 (2006.01)
Patent
CA 2518852
The present invention is directed to compounds that are antagonists of CGRP receptors and that are useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Cette invention concerne des composés qui constituent des antagonistes des récepteurs du CGRP et qui servent au traitement ou à la prévention de maladies dans lesquelles le CGRP intervient, telles que la céphalée, la migraine et la céphalée vasculaire de Horton. Cette invention concerne également des compositions pharmaceutiques contenant ces composés, ainsi que l'utilisation de ces composés et de ces compositions dans la prévention ou le traitement des maladies dans lesquelles le CGRP intervient.
Bell Ian M.
Gallicchio Steven N.
Theberge Cory R.
Williams Theresa M.
Zartman C. Blair
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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