Monocyte-derived dendritic cell subsets

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/06 (2006.01) A61K 9/00 (2006.01) A61K 39/385 (2006.01) A61K 48/00 (2006.01) A61K 35/12 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2394831

A novel subset of monocyte-derived dendritic cells are provided. Methods for producing these monocyte-derived dendritic cells and compositions comprising the dendritic cells of the invention are also provided. Methods for inducing an immune response to an antigen of interest using the dendritic cells of the invention are provided. Also provided are methods for therapeutically or prophylactically treating a disease in a subject suffering from the disease using the dendritic cells.

Cette invention concerne un ensemble de cellules dendritiques dérivées de monocytes ainsi que des méthodes permettant d'obtenir des cellules dendritiques dérivées de monocytes et des compostions renfermant lesdites cellules. L'invention porte sur des techniques propres à induire une réponse immunitaire contre un antigène d'intérêt au moyen des cellules dendritiques selon l'invention. Sont également décrites des méthodes de traitement ou de prévention d'une maladie au moyen de ces cellules dendritiques.

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