Monodisperse superparamagnetic particles for use in nucleic...

Details Monodisperse superparamagnetic particles for use in nucleic... Monodisperse superparamagnetic particles for use in nucleic...

C - Chemistry, Metallurgy

12

Q

150/3, 150/8.5

C12Q 1/68 (2006.01) C12N 15/10 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2003508

Monodisperse, superparamagnetic particles carrying a plurality of molecules of an oligonucleotide are disclosed and may be used inter alia for sequencing single stranded nucleic acids. The oligonucleotides may be covalently attached or affinity bonded to the particles either by their 3' or 5' termini. The particles have a specific gravity in the range 1.1 to 1.8 and axe 1 to 10 microns in diameter. A kit for the isolation and/or processing of target nucleic acid is also disclosed.

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