Monodispersed solid lipid particle compositions

A - Human Necessities – 61 – K

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A61K 9/113 (2006.01)

Patent

CA 2541009

The invention relates to a composition comprising a monodispersed lipid phase which is dispersed in a continuous aqueous phase, wherein the lipid phase comprises at least one crystallizable lipid, at least one active ingredient and at least one compound including two chains of fatty acids and one glycol polyethylene chain. The invention also relates to a method for the preparation of said compositions via a simple monodispersed O/W or O/W/O double emulsion.

L'invention concerne une composition comprenant une phase lipidique monodisperse dispersée dans une phase aqueuse continue, dans laquelle la phase lipidique comprend au moins un lipide cristallisable, au moins un principe actif et au moins un composé portant deux chaînes d'acides gras et une chaîne polyéthylène glycol. Elle concerne également le procédé de préparation de telles compositions via une émulsion simples H/E ou doubles E/H/E monodisperses.

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