Monofunctional glycosyltransferase gene of staphylococcus...

Details Monofunctional glycosyltransferase gene of staphylococcus... Monofunctional glycosyltransferase gene of staphylococcus...

C - Chemistry, Metallurgy

12

N

C12N 15/00 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C07K 1/00 (2006.01) C07K 14/00 (2006.01) C07K 17/00 (2006.01) C12N 9/10 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2275443

The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the MTG.

Cette invention concerne des composés d'acides nucléiques isolés qui codent une nouvelle glycosyltransférase monofonctionnelle (MTG) du Staphylococcus aureus; des vecteurs et des cellules hôtes hétérologues transformées, destinés à exprimer la MTG; ainsi qu'un procédé permettant d'identifier des composés qui se lient à l'activité enzymatique de MTG et/ou qui l'inhibent.

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