Monoglyceride/lactate ester permeation enhancer

A - Human Necessities – 61 – K

Patent

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Details

A61K 47/14 (2006.01) A61K 9/70 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/57 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2167526

A composition of matter for application to a body surface or membrane to administer a drug by permeation through the body surface or membrane, the composition comprising, in combination, the drug to be administered, in a therapeutically effective amount; and a permeation-enhancing mixture comprising a monoglyceride or a mixture of monoglycerides, and a lactate ester or a mixture of lactate esters.

Composition de substances s'appliquant à la surface d'un corps ou sur une membrane pour administrer un médicament par perméation à travers ces derniers. Ladite composition comprend une combinaison du médicament à administrer à dosage à effet thérapeutique et un mélange renforçateur de perméation comportant un monoglycéride ou un mélange de plusieurs d'entre eux, et un ester lactique ou un mélange de plusieurs esters de type lactate , présents dans des concentrations spécifiques.

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