Monoglyceride/lactate ester permeation enhancer for oxybutynin

Details Monoglyceride/lactate ester permeation enhancer for oxybutynin Monoglyceride/lactate ester permeation enhancer for oxybutynin

A - Human Necessities

61

K

A61K 47/14 (2006.01) A61K 9/70 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/57 (2006.01)

Patent

CA 2165802

A composition of matter for appli- cation to a body surface or membrane to administer oxybutynin by permeation through the body surface or membrane, the composition comprising, in combina- tion, the oxybutynin to be administered, in a therapeutically effective amount; and a permeation-enhancing mixture compris- ing a monoglyceride or a mixture of monoglycerides, and a lactic ester or a mixture of lactate esters; present in spe- cific concentrations.

Composition de substances s'appliquant à la surface d'un corps ou sur une membrane pour administrer de l'oxybutinine par perméation à travers ces derniers. Ladite composition comprend une combinaison de l'oxybutinine à administrer à dosage à effet thérapeutique et d'un mélange renforçateur de perméation comportant un monoglycéride ou un mélange de plusieurs d'entre eux, et un ester lactique ou un mélange de plusieurs esters de type lactate, présents dans des concentrations spécifiques.

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