Monohydrates of aminobenzenesulfonic acid derivatives and...

C - Chemistry – Metallurgy – 07 – D

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C07D 295/096 (2006.01) A61K 31/495 (2006.01) A61K 31/55 (2006.01) C07D 233/02 (2006.01) C07D 243/08 (2006.01) C07D 245/02 (2006.01) C07D 295/12 (2006.01) C07D 295/14 (2006.01)

Patent

CA 2192731

A monohydrate of an aminobenzenesulfonic acid derivative represented by the following formula (I), for example, 2-(1- piperazinyl)-5-methylbenzenesulfonic acid, which is substantially free from weight change due to moisture absorption, and can be weighed accurately in a manufacturing process of a pharmaceutical composition for the treatment of heart diseases comprising said monohydrate. (See formula I)

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