C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/10 (2006.01) A61P 1/06 (2006.01) A61P 31/14 (2006.01)
Patent
CA 2694363
Monomeric VHH domain derived from anti-VP6 camelid antibodies, dimeric domain, immunisation method, rotavirus detection method, vaccine composition, prevention and treatment methods for rotavirus infections, wherein said domain may be any of the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 or SEQ ID No. 4, and wherein said domains bind to protein VP6 of Group A rotavirus.
L'invention porte sur un domaine VHH monomérique dérivé d'anticorps anti-VP6 de camélidés, sur un domaine dimérique, sur un procédé d'immunisation, sur un procédé de détection de rotavirus, sur une composition vaccinale et sur des procédés de prévention et de traitement d'infections à rotavirus, ledit domaine pouvant être une quelconque séquence d'acides aminés parmi celles qui sont illustrées dans les SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3 ou SEQ ID No. 4, et lesdits domaines se liant à la protéine VP6 des rotavirus du groupe A.
Garaicoeachea Lorena Laura
Gomez Sebastian Silvia
Marcoppido Gisela Ariana
Martinez Escribano Jose Angel
Olichon Aurelien
Alternative Gene Expression S.l. (algenex)
Benoit & Cote Associes Inc.
Instituto Nacional de Tecnología Agropecuaria (inta)
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