Monospecific and multispecific antibodies and method of use

Details Monospecific and multispecific antibodies and method of use Monospecific and multispecific antibodies and method of use

C - Chemistry, Metallurgy

07

K

C07K 16/00 (2006.01)

Patent

CA 2696263

This invention relates to monospecific and multispecific antibodies that may be utilized for the diagnosis and treatment of various diseases. In addition, these antibodies may be modified by protease cleavage. Protease control or regulation may be provided by a protease site located in, for example, a linker. These protease-regulated antibodies may also be utilized for the diagnosis and treatment of various diseases.

La présente invention concerne des anticorps monospécifiques et multispécifiques qui peuvent être utilisés dans le diagnostic et le traitement de maladies variées. En outre, lesdits anticorps peuvent être modifiés par clivage de protéase. Un site de protéase situé par exemple dans un lieur peut exercer un contrôle ou une régulation des protéases. Ces anticorps régulés par les protéases peuvent également être utilisés dans le diagnostic et le traitement de maladies variées.

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