Monospecific polyclonal antibodies to shiga-like toxins

A - Human Necessities – 61 – K

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Details

A61K 39/395 (2006.01) C07K 14/245 (2006.01) C07K 16/12 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2132953

Disclosed herein are high titer, monospecific, polyclonal antibodies to Shiga- like toxins. Also disclosed are methods for producing such antibodies; compositions containing them, and methods for the diagnosis; prevention, and treatment of diseases caused by. Shiga-like toxins. These include hemiorrhagic colitis and hemolytic uremic syndrome in humans, edema disease in swine, and calf diarrhea in cattle:

Anticorps à titre élevé, monospécifiques, polyclonaux des toxines de type Shiga. L'invention porte également sur les méthodes d'obtention de tels anticorps, les compositions en renfermant et les méthodes de diagnostic, de prévention et de traitement des maladies causées par les toxines de type Shiga. Ces maladies sont notamment la colite hémorragique et le syndrome hémolytique et urémique chez l'homme, l'oedème chez les porcins et la diarrhée du veau chez les bovins.

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