Morphinan compounds

Details Morphinan compounds Morphinan compounds

C - Chemistry, Metallurgy

07

D

C07D 471/08 (2006.01) A61K 31/439 (2006.01) A61P 11/14 (2006.01) C07B 59/00 (2006.01)

Patent

CA 2685723

This disclosure relates to novel morphinan compounds and their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a .sigma.1 receptor agonist that also has NMDA antagonist activity.

Cette invention concerne de nouveaux composés de morphinane et leurs dérivés, des sels acceptables du point de vue pharmaceutique, des solvates et leurs hydrates. Cette description propose également des compositions comportant un composé de cette description et l'utilisation de telles compositions dans des procédés de traitement de maladies et d'affections qui sont traitées avantageusement par l'administration d'un agoniste de récepteur s1 qui a également une activité d'antagoniste de NMDA.

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