C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 489/08 (2006.01) A61K 31/485 (2006.01) A61P 25/04 (2006.01) A61P 25/20 (2006.01) C07D 489/00 (2006.01) C07D 489/02 (2006.01) C07D 489/04 (2006.01)
Patent
CA 2491689
The invention relates to a class of morphinan compounds and the quaternary ammonium salts thereof, substituted in position 14, which may be used as highly-active analgesics or also as opioid antagonists. The invention further relates to the pharmaceutically-acceptable salts and easily-produced derivatives thereof, a process for production thereof and use thereof in the production of pharmaceutical specialities.
La présente invention concerne une classe de composés de morphinane et leurs sels d'ammonium quaternaire substitués en position 14, ces composés pouvant être utilisés comme analgésiques à forte activité, mais aussi comme antagonistes opioïdes. L'invention concerne également des sels pharmaceutiquement acceptables et des dérivés facilement accessibles de ces composés, ainsi qu'un procédé de production de ces composés et leur utilisation pour produire des spécialités pharmaceutiques.
Greiner Elisabeth
Sailer Bettina
Schmidhammer Helmut
Schuellner Falko
Schuetz Johannes
Alcasynn Pharmaceuticals Gmbh
Borden Ladner Gervais Llp
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