Morphogen treatment of gastrointestinal ulcers

Details Morphogen treatment of gastrointestinal ulcers Morphogen treatment of gastrointestinal ulcers

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 6/00 (2006.01) A61K 38/17 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) C07K 14/51 (2006.01) C07K 16/22 (2006.01) A61F 2/00 (2006.01) A61K 38/00 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2144515

Disclosed are methods and compositions for maintaining the integrity of the gastrointestinal tract luminal lining in a mam- mal, including (1) limiting epithelial cell proliferation, (2) inhibiting ulcerative lesion formation, (3) inhibiting inflammation nor- mally associated with ulcerative diseases, and/or (4) stimulating the repair of ulcerative lesions and the regeneration of the lumi- nal tissue. The methods and compositions include a therapeutically effective amount of a morphogen as defined herein.

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