Morpholine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 413/06 (2006.01) C07D 265/30 (2006.01) C07D 265/32 (2006.01) C07D 303/22 (2006.01)

Patent

CA 1126731

ABSTRACT Morpholine derivatives of the formula Image (I) and their pharmaceutically acceptable acid addition salts[wherein R1 represents lower alkyl: R2 represents hydrogen, lower alkyl, benzyl, lower alkoxymethyl or an acyl group: R3 represents hydrogen, lower alkyl or phenyl; R4, R5 and R6 are independently hydrogen or lower alkyl and R7 is hydrogen, lower alkyl, lower alkenyl, lower alkynyl, aryl(lower)alkyl, tetrahydro- furylmethyl or cycloalkylmethyl] possess analgesic and/or opiate antagonistic activity.

361904

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