Morpholine derivatives and production thereof

C - Chemistry – Metallurgy – 07 – D

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260/200, 260/238

C07D 265/30 (2006.01) C07D 267/10 (2006.01)

Patent

CA 1065310

Abstract of the Disclosure Novel morpholine compounds of the formula: Image wherein R2 is hydrogen, methyl, ethyl, isopropyl, allyl, 2,2,2-trifluoroethyl, 2-hydroxyethyl, propargyl, benzyl, cyclo- propylmethyl, A is straight chain C2 or C3 alkylene group, B is -CH2-CH2-, -CH-CH- , Image , Image , -CH2-O-, -CH2-S-, -S- or -O-, ?D-E- is ?CH-CH2- or ?C=CH- and C1 and C2 are each 1,2-phenylene optionally substituted with chlorine and their non-toxic salts, which are useful as antidepressants and can be produced by various methods.

242957

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