Morpholino pyrimidine derivatives useful in the treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/04 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 239/42 (2006.01) C07D 413/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2660758

A compound of formula (I) or a pharamaceutically acceptable salt thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, for example in the treatment of proliferative disease such as cancer and particularly in disease mediated by an mTOR kinase and/or one or more PI3K enzyme.

La présente invention concerne un composé de formule (I) ou un sel de celui-ci pharmaceutiquement acceptable, des procédés pour les préparer, des compositions pharmaceutiques les contenant ainsi que leur utilisation thérapeutique, par exemple dans le traitement d'une maladie proliférative telle que le cancer et en particulier une maladie médiée par une mTOR kinase et/ou par une ou plusieurs enzymes PI3K.

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