Morpholinone compounds as factor ixa inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 265/30 (2006.01) A61K 31/4725 (2006.01) A61K 31/5355 (2006.01) A61K 31/54 (2006.01) A61K 31/553 (2006.01) A61P 7/00 (2006.01) C07D 265/32 (2006.01) C07D 267/10 (2006.01) C07D 279/06 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01)

Patent

CA 2745121

The present invention provides a compound of Formula (I) as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said com-pounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.

La présente invention porte sur un composé de Formule (I) tel que décrit présentement, ou sur un sel ou un solvate pharmaceutiquement acceptable de celui-ci. La présente invention porte également sur des compositions pharmaceutiques comprenant un ou plusieurs desdits composés, et sur des procédés d'utilisation desdits composés pour le traitement ou la prévention de thromboses, d'embolies, d'une hypercoagulabilité ou de changements fibrotiques.

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