Mosaic adenoviral vectors

Details Mosaic adenoviral vectors Mosaic adenoviral vectors

C - Chemistry, Metallurgy

12

N

C12N 7/01 (2006.01) A61K 39/235 (2006.01) C07H 21/00 (2006.01) C12N 15/00 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2445626

The present invention provides adenoviral vectors (Ad) that incorporate multiple distinct capsid modifications in a single virus particle, resulting in Ad that have improved gene delivery capacities and/or vector function.

L'invention porte sur des vecteurs adénoviraux (Ad) qui présentent de nombreuses modifications différentes de capside dans une seule particule de virus, si bien que les Ad ont amélioré leur capacité d'insertion de gène et/ou leur fonction de vecteur.

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