Mouse monoclonal antibody (5-21-3) to human immunodeficiency...

Details Mouse monoclonal antibody (5-21-3) to human immunodeficiency... Mouse monoclonal antibody (5-21-3) to human immunodeficiency...

C - Chemistry, Metallurgy

12

N

167/37, 195/1.10

C12N 15/18 (2006.01) C07K 16/10 (2006.01) C12N 15/16 (2006.01) G01N 33/569 (2006.01)

Patent

CA 1339489

The present invention discloses a monoclonal antibody capable of demonstrating specific reactivity with a conformational epitope on the Human Immunodeficiency Virus I protein gp41. The present invention also provides for a cell line capable of producing such a monoclonal antibody as well as immunological procedures for the detection in biological samples of exposure to HIV. The invention further provides for the use of the monoclonal antibody as a probe against native antigens and synthetic peptides of HIV.

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