Mouthwash and method of using same for the treatment of...

A - Human Necessities – 61 – K

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A61K 8/63 (2006.01) A61K 8/41 (2006.01) A61K 8/42 (2006.01) A61K 8/60 (2006.01) A61P 1/02 (2006.01) A61P 31/10 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2701583

An oral rinse formulation for the treatment or prophylaxis of mucositis or stomatitis comprises one or more of the following components in combination with pharmaceutically acceptable excipients or additives: a) at least one corticosteroid; b) at least one anti-histamine; c) at least one topical anaesthetic; and, d) at least one anti-fungal antibiotic agent. A stable nystatin containing formulation is also provided comprising a buffering agent, a preservative, a chelating agent and an anti-oxidant.

La présente invention a trait à une forme pharmaceutique de type bain de bouche, destinée au traitement ou à la prophylaxie d'une mucite ou d'une stomatite. Ladite forme pharmaceutique comprend un ou plusieurs des composants suivants en association avec des additifs ou des excipients acceptables sur le plan pharmaceutique : a) au moins un corticostéroïde ; b) au moins un antihistaminique ; c) au moins un anesthésique topique ; et, d) au moins un agent antibiotique antifongique. L'invention a également trait à une forme pharmaceutique stable contenant de la nystatine, ainsi qu'un agent tampon, un conservateur, un agent chélateur et un anti-oxydant.

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