Mptens as modifiers of the pten/igf pathway and methods of use

Details Mptens as modifiers of the pten/igf pathway and methods of use Mptens as modifiers of the pten/igf pathway and methods of use

C - Chemistry, Metallurgy

12

N

C12N 5/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2524148

Human MPTEN genes are identified as modulators of the PTEN/IGF pathway, and thus are therapeutic targets for disorders associated with defective PTEN/IGF function. Methods for identifying modulators of PTEN/IGF, comprising screening for agents that modulate the activity of MPTEN are provided.

Les gènes MPTEN humains sont identifiés comme des modulateurs de la voie PTEN/IGF, et sont donc des cibles thérapeutiques pour les troubles associés à une fonction PTEN/IGF déficiente. L'invention se rapporte à des procédés d'identification des modulateurs de PTEN/IGF, qui comprennent un criblage d'agents modulant l'activité du gène MPTEN.

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