Mptens as modifiers of the pten/igf pathway and methods of use

Details Mptens as modifiers of the pten/igf pathway and methods of use Mptens as modifiers of the pten/igf pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/00 (2006.01) C07H 21/04 (2006.01) C12Q 1/42 (2006.01)

Patent

CA 2527853

Human MPTEN genes are identified as modulators of the PTEN/IGF pathway, and thus are therapeutic targets for disorders associated with defective PTEN/IGF function. Methods for identifying modulators of PTEN/IGF, comprising screening for agents that modulate the activity of MPTEN are provided.

Selon l'invention, des gènes MPTEN humains ont été identifiés en tant que modulateurs du passage PTEN/IGF, et sont ainsi des cibles thérapeutiques pour des troubles liés à une déficience de la fonction PTEN/IGF. L'invention a également pour objet des procédés pour identifier des modulateurs de PTEN/IGF, comprenant des agents qui modulent l'activité de MPTEN.

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