Mracs as modifiers of the rac pathway and methods of use

Details Mracs as modifiers of the rac pathway and methods of use Mracs as modifiers of the rac pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C12Q 1/00 (2006.01) C12Q 1/48 (2006.01) G01N 33/53 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2518381

Human MRAC genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of MRAC are provided.

Des gènes MRAC humains sont identifiés comme modulateurs de la voie RB et sont, en conséquence, des cibles thérapeutiques pour des troubles associés à une fonction RAC défectueuse. L'invention concerne des procédés d'identification de modulateurs de RAC, comprenant la sélection d'agents modulant l'activité de MRAC.

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