C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07H 21/04 (2006.01) C07K 14/21 (2006.01) C12N 5/00 (2006.01) C12N 9/12 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12P 21/06 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2386235
Polynucleotides and polypeptides of Pseudomonas aeruginosa MraY, an enzyme involved in bacterial cell wall biosynthesis, are provided. The recombinant MraY enzyme is catalytically active in the first step of the membrane cycle of peptidoglycan biosynthesis. Also provided are proteins encoded by the sequences, host cells expressing the recombinant enzyme, and probes and primers.
La présente invention concerne des polynucléotides et des polypeptides de protéine Mray de Pseudomonas aéruginosa, et une enzyme intervenant dans la biosynthèse de la paroi cellulaire bactérienne. Cette enzyme Mray recombinante est catalytiquement active dans la première étape du cycle membranaire de la biosynthèse du peptidoglycane. Cette invention concerne aussi des protéines codées par ces séquences, des cellules hôtes exprimant cette enzyme recombinante, des sondes et des amorces.
Azzolina Barbara
El-Sherbeini Mohamed
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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