Msc-megakaryocyte precursor composition and method of...

A - Human Necessities – 01 – N

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A01N 1/02 (2006.01) A61K 35/28 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2271758

The present invention is directed to isolated and purified human mesenchymal stem cells, to a method for isolating, purifying, and culturally expanding human mesenchymal stem cells (i.e. mesenchymal stem cells or "MSCs"), and to the characterization of and uses for such cells. In particular, the invention relates to isolation of MSCs that are associated with hematopoietic cells, such as megakaryocyte precursors, in the bone marrow.

L'invention concerne des cellules souches mésanchymateuses isolées et purifiées d'origine humaine, un procédé pour isoler, purifier et cultuver les cellules souches mésanchymateuses d'origine humaine (également appelées cellules MSC), ainsi que la caractérisation et les utilisations de ces cellules. En particulier, l'invention concerne l'isolement de cellules MSC qui sont associées avec des cellules hématopoïétiques, telles que les précurseurs des mégacaryocytes de la moelle osseuse.

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