Msh5 ablated mice and uses therefor

A - Human Necessities – 01 – K

Patent

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Details

A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 49/00 (2006.01) C07K 14/82 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2355631

An animal, e.g., transgenic mouse, in which the MSH5 gene is misexpressed. The animal is useful for screening treatments for a number of conditions. Methods for identifying contraceptive agents are also described.

La présente invention concerne un animal, par exemple une souris transgénique, chez lequel le gène MSH5 est mal exprimé. On utilise cet animal pour cribler et rechercher des traitements destinés à un certain nombre de pathologies. L'invention concerne aussi des procédés permettant d'identifier des agents contraceptifs.

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